Gifford Bioscience is a UK-based contract research organisation (CRO) specializing in receptor pharmacology and occupancy for neurology, oncology and metabolic diseases. Our receptor-ligand binding assays provide critical insight for early stage drug discovery and preclinical research.

Our PhD level scientists are experts in gold-standard radiometric methods and in advanced label-free, kinetic affinity techniques. Our customized assays use human tissue, animal tissues, cultured cells, membranes and recombinant proteins. We work with leading pharma, biotech and university researchers worldwide.

Determination of receptor affinities and ligand binding parameters for test compounds in a tissue homogenate or cell preparation.

Imaging the distribution of a labeled test drug in tissue sections. Quantification of ligand binding in regions of interest.

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Measurement of the degree to which a test compound engages its target receptor in tissues or in an animal.

Measurement of a compounds transport into cells or efflux from cells. Determination of a compound’s potency and efficacy.

Kinetic, label-fee measurement of a drug’s affinity for its receptor using Surface Plasmon Resonance (SPR).

Measurement of second messenger levels resulting from ligand binding. Determination of potency and efficacy of compounds and identification of agonists and antagonists.

Additional Services

as part of a core receptor pharmacology study

Ancillary Services

as part of a core receptor pharmacology study

Custom Radiolabeling

Human and Animal Tissue

ELISAs

Cell Culture & Transfections

Who We Are

Since 2017, we have been building our reputation as the experts in receptor ligand binding.

87% recurring customers

53% US customers, 33% in Europe

100% PhD level scientists

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Copyright © 2024 Gifford Bioscience Limited
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Copyright © 2024 Gifford Bioscience Limited
Privacy Policy